Gospel choir A-flame, who competed in the BBC1 series Pitch Battle, will perform at the Salmon Youth Centre concert on Saturday, September 23.
Members of the Salmon Youth Centre and other local acts will also perform at the concert.
The concert is being held to honour the 50th anniversary of St James Church, Bermondsey, originally started by volunteers from the centre.
The thanksgiving and celebration concert is on at the centre, 43 Old Jamaica Road, Bermondsey, SE16 4TE on Saturday September 23, 7-9pm.
Admission is free.